Milk Thistle

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crowsandcats
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Joined: Tue Jan 10, 2012 11:22 pm

Milk Thistle -

Post by crowsandcats » Sun Jan 08, 2006 10:24 am

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FROM : A-Z of Natural Remedies

Publisher : Blitz Editions
ISBN : 1 85605 282 6
General Editor : Amanda Sandeman

Clinical use of milk thistle for poisoning from the Death Cap toadstool has proved especially interesting. When eaten, this fungus releases two potent liver-damaging substances that, on average, prove lethal in 30-40 per cent of cases, even when victoms are treated with all the techniques modern medicine has at its disposal.

In a 1970's trial carried out in Germany by Dr Vogel, a leading researcher into Silymarin, 60 patients suffering from severe Amanitine poisoning were treated with milk thistle extract. All the patients survived, and Dr Vogel declared that the results ranged 'from amazing to spectacular'.

Research findings
The active ingredients in milk thistle include a digestive 'bitter' principle, flavonolignans, and a flavonoid, known as silymarin. The first of these partly accounts for its use in folk medicine in the treatment of apetite loss and digestive problems. The latter two - paricularly silymarin - are associated with its benefits to an ailing liver. Numerous trials have been carried out to determine the full scope of its therapeutic value. At present, it is known to prevent or greatly reduce the extent of liver damage caused by several potent toxins including carbon tetrachloride (used as a solvent in industry and in a number of specialist dry-cleaning process), poison from amanita phalloides, thiocetamide (a substance that can cause cirrhosis-type damage to the liver), and various heavy metals.

The way it works
When the active constituents of milk thistle are absorbed by the digestive system, the concentration in the bile exceeds that in the blood, suggesting that they selectively accumulate in the liver. Its beneficial effects on that organ seem to be threefold:

1. Simulation of protein synthesis. This partly accounts for milk thistle's ability to regenerate damaged liver tissue.
2. Inhibition of leukotriene and inflammatory prostaglandin formation. Both classes of compound are released in response to chemical and other varieties of liver damage, and help to bring about the resultant inflammation which, itself, can lead to further damage.
3. The antioxidant activity of milk thistle has been shown to be considerably stronger even than that of vitamin E. Extracts from the plant are thought to be capable of counteracting the damaging effects of free radicals - supercharged fragments of molecules that are capable of harming living tissue and causing degenerative diseases and cancer.



Thistle on trial
Hundreds of scientific studies now confirm the therapeutic value of milk thistle. No damaging side-effects have been recorded in its application over the years in Europe to treat a variety of liver conditions. Trials involving more than 2000 patients with some type of liver disorder have shown it to be useful in treating: alcohol and chemical induced fatty liver, cirrhosis, chronic hepatitis, cholangitis (inflammation of the bile ducts), pericholangitis (inflamation of the tissue around the bile ducts) and hepatic parenchymal changes (damage to the parenchymal tissues of the liver). All these benefits have been confirmed by clinical, laboratory and histological (tissue) studies. On a less crucial level, milk thistle can be used as a nutritional supplement to promote helath by protecting the liver against the many adverse factors that can cause damage to the vital organ.
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Obviously it differs from plant to plant, person to person and mushroom to mushroom, but does anybody have any idea for dosages in terms of amount of seeds, to prevent, say the negative effects of eating one cap of A. phalloides?

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420_4life
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Location: Canada

Re: Milk Thistle -

Post by 420_4life » Sun Jan 08, 2006 10:31 am

I have almost botten milk thistle seeds a few times, the only reason is because i dont really have any nice place outside to plant it. I have heard many good things about milk thistle, the natives used in as a healing treatment i believe.

its good stuff
cool to see growing, iv seen it a few times up north

peace
jackpot

crowsandcats
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Re: Milk Thistle -

Post by crowsandcats » Sun Jan 08, 2006 1:51 pm

It might enjoy being planted on roadsides or other "disturbed" sites.

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hekura
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Re: Milk Thistle -

Post by hekura » Sun Jan 08, 2006 2:57 pm

Since we're on the topic of liver damage: what, besides poisonous mushrooms, would be most damaging to your liver over a long period of time?

I know heavy alcohol use would. I'm in the habit of drinking 4-6 Bud Lites a day. I like the alcohol buzz, but I rarely drink liquor and sometimes wine.

Maybe a good milk thistle/ charcoal/ laxative cleanse would be good once in a while?

Btw, I have read that your liver can repair itself pretty easily if given the chance(of course, not if you've eaten one of those seriously poisonous mushrooms) and that drugs like Tylenol aren't really that damaging until you get past 4 grams a day.

It would also be nice to go to the mushroom page and enjoy a discussion about what poisonous mushrooms to look out for.

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420_4life
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Re: Milk Thistle -

Post by 420_4life » Sun Jan 08, 2006 7:33 pm

Tylenol is damaging to your body much less than 4 grams a day. Think about it, how much chemicals your body has to process to get your body clean. Morphine you take about 30mg lets say, and acetaminophen you take 500mg, holy fuck, which is better for your body...morphine.

Any drug that takes 500mg to feel effects is not good in my books, i dont like to take anything that requires more than 100mg to have effects. I like the potent ones that nature gave us so potent for a reason, so taking our brain that far doesnt hurt our body.

peace
jackpot

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PeaceOfMind
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Location: Lonesome ocean.

Re: Milk Thistle -

Post by PeaceOfMind » Mon Jan 09, 2006 11:16 pm

Milk Thistle's a mean lady... when handling/harvesting definately use care. Her spikes'll tear you open quickly.

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jbmac
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Re: Milk Thistle -

Post by jbmac » Sat Aug 26, 2006 8:58 pm

420_4life wrote:Tylenol is damaging to your body much less than 4 grams a day.
jackpot
Amen - and if you drink with Tylenol, any amount might damage your liver.

Back to Milk Thistle, is there any hard evidence it helps to use milk thistle before and after moderate drinking of our wonderful, revenue producing, goverment supported and taxed buddy, booze?

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Merkabaster
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Re: Milk Thistle -

Post by Merkabaster » Sun Aug 27, 2006 2:23 am

420, reading your post was a life altering experience.

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mourningdove
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Re: Milk Thistle -

Post by mourningdove » Sun Aug 27, 2006 2:29 pm

dandoline root has similar benefits...

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TooStonedToType
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Location: Colorado

Re: Milk Thistle -

Post by TooStonedToType » Sun Aug 27, 2006 2:57 pm

Here's an interesting study I found while investigating ergothioneine.

Title: L-ergothioneine, Milk thistle, and S-adenosylmethionine for the prevention, treatment and repair of liver damage

http://www.pharmcast.com/Patents/Yr2...iver042903.htm

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