Reported to be active both sublingually and smoked, with effects being compared to cannabis.
Anyone have any experience with this plant? The only chemical constituents I could find, mention hyaluronidase inhibition. I do not see that as the answer to why the plant may produce euphoria or cannabis like effects.
From pubmed - "From the extract, four new phenylpropanoids, two new maltol glycosides, two new monoterpene glycosides, and two new phenolic compounds were isolated together with 19 known compounds. Among these constituents, two phenylpropanoids and a flavone glucuronide were revealed as hyaluronidase inhibitors."
Image not my own, found on google.
Here is the GOE section from Snu:
Keiskea japonica Miq. – shimobashira
This Japanese mint was recently discovered to be psychoactive during
a small wave of experimentation with members of the family Labiatae,
following discovery of the activity of diterpenes from Salvia divinorum.
Taken sublingually, 4-5 of the large, bitter leaves were active after being
held in the mouth for at least 10 minutes. The effects are reportedly similar
to the other ‘lesser-active’ Salvia spp. [as opposed to the highly-active
S. divinorum], and consist of a mild euphoria and ‘Cannabis-like’ effects,
as well as disturbing balance (pers. comm.). The herb is also mildly psychoactive
when smoked, although the sample which I bioassayed was at
least 5 years old. Fresher material may have been subjectively stronger in
effect. The only side effect noted was a mild headache, which might perhaps
have been due to the age of the sample (pers. obs.).
Keiskea japonica is a perennial herb; stems c.60cm long, 4-angled,
slightly pilose or glabrous, often branched in upper part. Leaves opposite,
toothed, thinly chartaceous, broadly lanceolate to narrowly ovate,
6-15(-20) x 2-5.5cm, apex abruptly long-acuminate, base long-acuminate,
rarely subobtuse, margin acutely toothed except near base, puberulent
on midrib above, glabrous or thinly pilose on nerves beneath; petioles
5-30mm long. Verticils 2-fl owered, forming 1-sided spikes 5-12cm
long, shortly pilose; bracts broadly linear, small, persistent; fl owers bisexual,
pedicelled; calyx deeply 5-toothed, actinomorphic, campanulate,
with lanceolate lobes, hairy on throat, 3mm long at anthesis, 5-6mm long
in fruit, nearly as long as pedicels, exceeding the bracts; corolla white,
c.7mm long, shallowly lobed, tube broadened in upper part, with ring
of hairs inside, limb slightly bilabiate, lower lip 3-lobed, midlobe slightly
larger; stamens 4, didymous, exserted, upper pair shorter, fi laments glabrous;
anthers 2-locular. Ovary superior, deeply 4-lobed; style solitary, gynobasic;
ovules 4, erect. Nutlets usually solitary, globose, dark brown, 1.5-
2mm across, with darker reticulations. Fl. Sep.-Oct.
Mountains; Honshu [Kanto district and westward], Shikoku, Kyushu
[Japan] (Ohwi 1965).